07.04A · Les parasites — diapositives

Parasites — slides

SMB1 De la molécule à la cellule Introduction à la microbiologie · 46 pages

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Parasites — Title

1Parasites — Title

2Course Outline

Concept of Parasitism

3Concept of Parasitism 4Definition of a Parasite 5Biological Relationships Compared 6Infection vs Disease 7Consequences for the Host 8Parasite Microscopy Scale

Diversity of Parasites

9Diversity of Parasites 10Size Scale of Infectious Agents 11Facultative vs Obligate Parasitism 12Intracellular Parasitism 13Unicellular vs Multicellular 14Major Parasitic Infections in Numbers 15Eukaryotic Phylogenetic Tree

Life Cycles and Dissemination

16Life Cycles and Dissemination 17Life Cycle Complexity 18Reservoirs and Transmission Modes 19Giardia intestinalis Cycle 20Plasmodium Infection Cycle 21Toxoplasma gondii and Pregnancy 22Accidental Host — Swimmer's Itch

Parasites as Manipulators

23Parasites as Manipulators 24T. brucei — Parasitemia Waves 25T. brucei — Antigenic Variation Mechanism 26T. brucei — VSG Gene Switching 27Plasmodium — Host Cell Surface Modification 28Plasmodium — RBC Knobs and PfEMP1 29Plasmodium — PfEMP1 Receptor Binding 30Plasmodium — Cytoadherence and Sequestration 31Malaria and Sickle-Cell Selection 32Toxoplasma — Tachyzoite vs Bradyzoite 33Toxoplasma — Behavioral Test Setup 34Toxoplasma — Altered Predator Aversion

Fighting Parasitic Diseases

35Fighting Parasitic Diseases 36Control Strategies Overview 37Quiz — Best Malaria Prevention 38Bed Nets and Malaria Deaths 39Vector Control Methods 40Antimalarial Drug Targets 41WHO — Artemisinin Combination Therapy 42Malaria Mortality — 20th Century 43Malaria Vaccines — RTS,S and R21 44New Targets — Plasmepsins IX and X

Learning Objectives

45Learning Objectives

07.04APage 1Parasites — Title

Les parasites — diapositives page 1

07.04APage 2Course Outline

Les parasites — diapositives page 2

07.04APage 3Concept of Parasitism

Les parasites — diapositives page 3

07.04APage 4Concept of ParasitismDefinition of a Parasite

Les parasites — diapositives page 4

07.04APage 5Concept of ParasitismBiological Relationships Compared

Les parasites — diapositives page 5

07.04APage 6Concept of ParasitismInfection vs Disease

Les parasites — diapositives page 6

07.04APage 7Concept of ParasitismConsequences for the Host

Les parasites — diapositives page 7

07.04APage 8Concept of ParasitismParasite Microscopy Scale

Les parasites — diapositives page 8

07.04APage 9Diversity of Parasites

Les parasites — diapositives page 9

07.04APage 10Diversity of ParasitesSize Scale of Infectious Agents

Les parasites — diapositives page 10

07.04APage 11Diversity of ParasitesFacultative vs Obligate Parasitism

Les parasites — diapositives page 11

07.04APage 12Diversity of ParasitesIntracellular Parasitism

Les parasites — diapositives page 12

07.04APage 13Diversity of ParasitesUnicellular vs Multicellular

Les parasites — diapositives page 13

07.04APage 14Diversity of ParasitesMajor Parasitic Infections in Numbers

Les parasites — diapositives page 14

07.04APage 15Diversity of ParasitesEukaryotic Phylogenetic Tree

Les parasites — diapositives page 15

07.04APage 16Life Cycles and Dissemination

Les parasites — diapositives page 16

07.04APage 17Life Cycles and DisseminationLife Cycle Complexity

Les parasites — diapositives page 17

07.04APage 18Life Cycles and DisseminationReservoirs and Transmission Modes

Les parasites — diapositives page 18

07.04APage 19Life Cycles and DisseminationGiardia intestinalis Cycle

Les parasites — diapositives page 19

07.04APage 20Life Cycles and DisseminationPlasmodium Infection Cycle

Les parasites — diapositives page 20

07.04APage 21Life Cycles and DisseminationToxoplasma gondii and Pregnancy

Les parasites — diapositives page 21

07.04APage 22Life Cycles and DisseminationAccidental Host — Swimmer's Itch

Les parasites — diapositives page 22

07.04APage 23Parasites as Manipulators

Les parasites — diapositives page 23

07.04APage 24Parasites as ManipulatorsT. brucei — Parasitemia Waves

Les parasites — diapositives page 24

07.04APage 25Parasites as ManipulatorsT. brucei — Antigenic Variation Mechanism

Les parasites — diapositives page 25

07.04APage 26Parasites as ManipulatorsT. brucei — VSG Gene Switching

Les parasites — diapositives page 26

07.04APage 27Parasites as ManipulatorsPlasmodium — Host Cell Surface Modification

Les parasites — diapositives page 27

07.04APage 28Parasites as ManipulatorsPlasmodium — RBC Knobs and PfEMP1

Les parasites — diapositives page 28

07.04APage 29Parasites as ManipulatorsPlasmodium — PfEMP1 Receptor Binding

Les parasites — diapositives page 29

07.04APage 30Parasites as ManipulatorsPlasmodium — Cytoadherence and Sequestration

Les parasites — diapositives page 30

07.04APage 31Parasites as ManipulatorsMalaria and Sickle-Cell Selection

Les parasites — diapositives page 31

07.04APage 32Parasites as ManipulatorsToxoplasma — Tachyzoite vs Bradyzoite

Les parasites — diapositives page 32

07.04APage 33Parasites as ManipulatorsToxoplasma — Behavioral Test Setup

Les parasites — diapositives page 33

07.04APage 34Parasites as ManipulatorsToxoplasma — Altered Predator Aversion

Les parasites — diapositives page 34

07.04APage 35Fighting Parasitic Diseases

Les parasites — diapositives page 35

07.04APage 36Fighting Parasitic DiseasesControl Strategies Overview

Les parasites — diapositives page 36

07.04APage 37Fighting Parasitic DiseasesQuiz — Best Malaria Prevention

Les parasites — diapositives page 37

07.04APage 38Fighting Parasitic DiseasesBed Nets and Malaria Deaths

Les parasites — diapositives page 38

07.04APage 39Fighting Parasitic DiseasesVector Control Methods

Les parasites — diapositives page 39

07.04APage 40Fighting Parasitic DiseasesAntimalarial Drug Targets

Les parasites — diapositives page 40

07.04APage 41Fighting Parasitic DiseasesWHO — Artemisinin Combination Therapy

Les parasites — diapositives page 41

07.04APage 42Fighting Parasitic DiseasesMalaria Mortality — 20th Century

Les parasites — diapositives page 42

07.04APage 43Fighting Parasitic DiseasesMalaria Vaccines — RTS,S and R21

Les parasites — diapositives page 43

07.04APage 44Fighting Parasitic DiseasesNew Targets — Plasmepsins IX and X

Les parasites — diapositives page 44

07.04APage 45Learning Objectives

Les parasites — diapositives page 45

07.04APage 46Closing

Les parasites — diapositives page 46