10A.06 · Fonction cardiaque

Cardiac function

Système circulatoire · 47 pages

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Cardiac Function

1Cardiac Function 2Learning Objectives 3Course Outline

Anatomy & Histology Review

4Two Circulations in Series 5Heart Chambers & Great Vessels 6Heart Valves 7Valve Open/Close States 8Striated Muscle Types 9Cardiomyocyte vs Skeletal Myocyte — Ultrastructure 10Cardiomyocyte vs Skeletal Myocyte — Summary Table 11No Tetanus in Cardiac Muscle 12Cardiac Cell — Intercalated Disks & Gap Junctions 13Functional Structure of Cardiomyocyte 14Cardiac Growth & Hypertrophy

15Course Outline

Conduction System & Heart Rate Regulation

16SA Node & Automaticity 17Conduction Pathway & Velocities

18Course Outline

Cardiac Cycle & Graphical Representations

19Five Phases of the Cardiac Cycle 20Valve Timing in the Cardiac Cycle 21Simplified Wiggers Diagram 22Illustrated Wiggers Diagram 23ECG & Heart Sounds (S1/S2)24Right vs Left Heart Pressures 25Excitation-Contraction Coupling & ECG 26Wiggers to Pressure-Volume Diagram 27Reading a P-V Diagram 28Wiggers ↔ P-V Diagram Correspondence 29P-V Diagram Interpretation — EDV, ESV, EF, ESPVR

30Course Outline

Determinants of Cardiac Output

31Blood Redistribution Principles 32Cardiac Output = SV × HR 33Laplace Law — Wall Stress Physics 34Laplace Law — Relaxation vs Contraction 35Why Skeletal Force Mechanisms Fail in Heart 36Tension-Length Relationship & Preload 37Frank-Starling Law & Preload Definition 38Frank-Starling — Right = Left Output 39Family of Frank-Starling Curves 40Frank-Starling → Cardiac Function Curve 41Afterload — Laplace During Contraction 42Afterload — Systolic Laplace Tension 43Inotropy — Calcium & β1-Adrenergic Pathway 44Inotropy Shifts ESPVR on P-V Loop 45Autonomic Nervous System & Inotropy 46Summary — Preload, Afterload, Inotropy on P-V Loop 47Cardiac Output Regulation Recap

10A.06Page 1Cardiac Function

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10A.06Page 2Cardiac FunctionLearning Objectives

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10A.06Page 3Cardiac FunctionCourse Outline

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10A.06Page 4Cardiac FunctionAnatomy & Histology ReviewTwo Circulations in Series

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10A.06Page 5Cardiac FunctionAnatomy & Histology ReviewHeart Chambers & Great Vessels

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10A.06Page 6Cardiac FunctionAnatomy & Histology ReviewHeart Valves

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10A.06Page 7Cardiac FunctionAnatomy & Histology ReviewValve Open/Close States

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10A.06Page 8Cardiac FunctionAnatomy & Histology ReviewStriated Muscle Types

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10A.06Page 9Cardiac FunctionAnatomy & Histology ReviewCardiomyocyte vs Skeletal Myocyte — Ultrastructure

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10A.06Page 10Cardiac FunctionAnatomy & Histology ReviewCardiomyocyte vs Skeletal Myocyte — Summary Table

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10A.06Page 11Cardiac FunctionAnatomy & Histology ReviewNo Tetanus in Cardiac Muscle

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10A.06Page 12Cardiac FunctionAnatomy & Histology ReviewCardiac Cell — Intercalated Disks & Gap Junctions

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10A.06Page 13Cardiac FunctionAnatomy & Histology ReviewFunctional Structure of Cardiomyocyte

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10A.06Page 14Cardiac FunctionAnatomy & Histology ReviewCardiac Growth & Hypertrophy

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10A.06Page 15Cardiac FunctionCourse Outline

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10A.06Page 16Cardiac FunctionConduction System & Heart Rate RegulationSA Node & Automaticity

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10A.06Page 17Cardiac FunctionConduction System & Heart Rate RegulationConduction Pathway & Velocities

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10A.06Page 18Cardiac FunctionCourse Outline

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10A.06Page 19Cardiac FunctionCardiac Cycle & Graphical RepresentationsFive Phases of the Cardiac Cycle

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10A.06Page 20Cardiac FunctionCardiac Cycle & Graphical RepresentationsValve Timing in the Cardiac Cycle

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10A.06Page 21Cardiac FunctionCardiac Cycle & Graphical RepresentationsSimplified Wiggers Diagram

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10A.06Page 22Cardiac FunctionCardiac Cycle & Graphical RepresentationsIllustrated Wiggers Diagram

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10A.06Page 23Cardiac FunctionCardiac Cycle & Graphical RepresentationsECG & Heart Sounds (S1/S2)

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10A.06Page 24Cardiac FunctionCardiac Cycle & Graphical RepresentationsRight vs Left Heart Pressures

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10A.06Page 25Cardiac FunctionCardiac Cycle & Graphical RepresentationsExcitation-Contraction Coupling & ECG

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10A.06Page 26Cardiac FunctionCardiac Cycle & Graphical RepresentationsWiggers to Pressure-Volume Diagram

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10A.06Page 27Cardiac FunctionCardiac Cycle & Graphical RepresentationsReading a P-V Diagram

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10A.06Page 28Cardiac FunctionCardiac Cycle & Graphical RepresentationsWiggers ↔ P-V Diagram Correspondence

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10A.06Page 29Cardiac FunctionCardiac Cycle & Graphical RepresentationsP-V Diagram Interpretation — EDV, ESV, EF, ESPVR

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10A.06Page 30Cardiac FunctionCourse Outline

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10A.06Page 31Cardiac FunctionDeterminants of Cardiac OutputBlood Redistribution Principles

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10A.06Page 32Cardiac FunctionDeterminants of Cardiac OutputCardiac Output = SV × HR

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10A.06Page 33Cardiac FunctionDeterminants of Cardiac OutputLaplace Law — Wall Stress Physics

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10A.06Page 34Cardiac FunctionDeterminants of Cardiac OutputLaplace Law — Relaxation vs Contraction

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10A.06Page 35Cardiac FunctionDeterminants of Cardiac OutputWhy Skeletal Force Mechanisms Fail in Heart

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10A.06Page 36Cardiac FunctionDeterminants of Cardiac OutputTension-Length Relationship & Preload

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10A.06Page 37Cardiac FunctionDeterminants of Cardiac OutputFrank-Starling Law & Preload Definition

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10A.06Page 38Cardiac FunctionDeterminants of Cardiac OutputFrank-Starling — Right = Left Output

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10A.06Page 39Cardiac FunctionDeterminants of Cardiac OutputFamily of Frank-Starling Curves

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10A.06Page 40Cardiac FunctionDeterminants of Cardiac OutputFrank-Starling → Cardiac Function Curve

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10A.06Page 41Cardiac FunctionDeterminants of Cardiac OutputAfterload — Laplace During Contraction

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10A.06Page 42Cardiac FunctionDeterminants of Cardiac OutputAfterload — Systolic Laplace Tension

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10A.06Page 43Cardiac FunctionDeterminants of Cardiac OutputInotropy — Calcium & β1-Adrenergic Pathway

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10A.06Page 44Cardiac FunctionDeterminants of Cardiac OutputInotropy Shifts ESPVR on P-V Loop

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10A.06Page 45Cardiac FunctionDeterminants of Cardiac OutputAutonomic Nervous System & Inotropy

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10A.06Page 46Cardiac FunctionDeterminants of Cardiac OutputSummary — Preload, Afterload, Inotropy on P-V Loop

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10A.06Page 47Cardiac FunctionDeterminants of Cardiac OutputCardiac Output Regulation Recap

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