09E.11Page 1Introduction
09E.11 · Cellules souches et thérapie cellulaire
Stem cells and cell therapy
Mécanisme du développement · 74 pages
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09E.11Page 2Regenerative MedicineTarget Diseases
09E.11Page 3Regenerative MedicineCell Therapy Defined
09E.11Page 4Regenerative MedicineTwo Approaches
09E.11Page 5Stem Cell BiologyStem Cell Definition
09E.11Page 6Stem Cell BiologyDifferentiation Potential
09E.11Page 7Stem Cell BiologyCell Hierarchy
09E.11Page 8Stem Cell BiologyCellular Reprogramming
09E.11Page 9Adult Stem CellsTissue Repair Pools
09E.11Page 10Adult Stem CellsSelf-Renewal Mechanism
09E.11Page 11Adult Stem CellsLeukemia Treatment
09E.11Page 12Adult Stem CellsCord & Placenta Sources
09E.11Page 13Embryonic Stem CellsIntroduction
09E.11Page 14Embryonic Stem CellsBlastocyst Anatomy
09E.11Page 15Embryonic Stem CellsES Cell Derivation
09E.11Page 16Embryonic Stem CellsES Cell Pluripotency
09E.11Page 17Embryonic Stem CellsOrganoids & 3D Models
09E.11Page 18Cell Therapy: DiabetesOverview
09E.11Page 19Cell Therapy: DiabetesDiabetes Types
09E.11Page 20Cell Therapy: DiabetesPancreas Anatomy
09E.11Page 21Cell Therapy: DiabetesIslet Cell Types
09E.11Page 22Cell Therapy: DiabetesCell Therapy Goal
09E.11Page 23Cell Therapy: DiabetesEdmonton Protocol
09E.11Page 24Therapeutic Cloning (SCNT)SCNT Principle
09E.11Page 25Therapeutic Cloning (SCNT)Primate Cloning
09E.11Page 26Therapeutic Cloning (SCNT)Human NT-ESC (2013)
09E.11Page 27Therapeutic Cloning (SCNT)Diabetic Patient SCNT
09E.11Page 28Therapeutic Cloning (SCNT)T1D Therapy via SCNT
09E.11Page 29Cell Therapy: DiabetesIn Vitro β Cell Generation
09E.11Page 30Therapeutic Cloning (SCNT)Personalized Stem Cells
09E.11Page 32Induced Pluripotent Stem CellsiPS Cell Concept
09E.11Page 35Induced Pluripotent Stem CellsClinical Applications
09E.11Page 36Induced Pluripotent Stem CellsiPS & Diabetes Therapy
09E.11Page 37Induced Pluripotent Stem CellsKidney Organoids
09E.11Page 38Induced Pluripotent Stem CellsClinical Trial (2024)
09E.11Page 40Cell Therapy: DiabetesSurrogate Cell Strategy
09E.11Page 41Emerging ApplicationsFemale Infertility (Mouse)
09E.11Page 42Emerging ApplicationsHuman Oogonia from iPS
09E.11Page 43Emerging ApplicationsHuman Oocytes via SCNT (2025)
09E.11Page 44Emerging ApplicationsBipaternal Embryos
09E.11Page 45Genome Editing (CRISPR/Cas9)Mechanism
09E.11Page 46Genome Editing (CRISPR/Cas9)Nobel Prize 2020
09E.11Page 47Genome Editing (CRISPR/Cas9)Ethical Risks: Eugenics
09E.11Page 48Genome Editing (CRISPR/Cas9)He Jiankui Case
09E.11Page 49Genome Editing (CRISPR/Cas9)In Vivo HITI Therapy
09E.11Page 50Genome Editing (CRISPR/Cas9)Sickle Cell Therapy
09E.11Page 51Emerging ApplicationsPig–Human Chimeras
09E.11Page 52Regenerative MedicineApproaches Summary
09E.11Page 53Intrinsic RegenerationLiver Regeneration
09E.11Page 54Intrinsic RegenerationPancreatic Regeneration?
09E.11Page 55Intrinsic RegenerationExperimental Models
09E.11Page 56Intrinsic RegenerationAblation & Lineage Tracing
09E.11Page 57Intrinsic RegenerationTransgenic Mouse Production
09E.11Page 58Intrinsic Regenerationβ Cell Ablation Model
09E.11Page 59Intrinsic RegenerationRIP-DTR Transgene
09E.11Page 60Intrinsic RegenerationDT Mechanism
09E.11Page 61Intrinsic Regenerationβ Cell Elimination Result
09E.11Page 62Intrinsic RegenerationInsulin Cell Recovery
09E.11Page 63Intrinsic RegenerationOrigin of New β Cells?
09E.11Page 64Intrinsic Regenerationα Cell Lineage Tracing
09E.11Page 65Intrinsic Regenerationα Cell Marking Confirmed
09E.11Page 66Intrinsic Regenerationα→β Conversion Test
09E.11Page 67Intrinsic RegenerationBihormonal Cell Evidence
09E.11Page 68Intrinsic Regenerationα→β Conversion Conclusion
09E.11Page 69Intrinsic RegenerationCell Identity Maintenance
09E.11Page 70Intrinsic RegenerationHuman Pancreas Plasticity
09E.11Page 71Intrinsic RegenerationRare β Cells in T1D
09E.11Page 72Intrinsic RegenerationHuman Non-β Reprogramming
09E.11Page 73Intrinsic RegenerationRegeneration Summary
09E.11Page 74Closing
