12.01 · Cours 1 — Développement du système immunitaire
Course 1 — Immune system development
SMB4 Systèmes physiologiques 2 Immunologie, inflammation, transplantation · 60 pages
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12.01Page 3Immune System DevelopmentTitle Slide
12.01Page 14Immune System DevelopmentHematopoiesisStem Cells and DevelopmentOne Stem Cell per Lineage?
12.01Page 15Immune System DevelopmentHematopoiesisStem Cells and DevelopmentLymphoid and Myeloid Stem Cells
12.01Page 16Immune System DevelopmentHematopoiesisStem Cells and DevelopmentSimplified Hematopoietic Tree
12.01Page 18Immune System DevelopmentHematopoiesisStem Cells and DevelopmentLong-Term Reconstitution Assay
12.01Page 19Immune System DevelopmentHematopoiesisStem Cells and DevelopmentSingle HSC Reconstitution Proof
12.01Page 20Immune System DevelopmentHematopoiesisStem Cells and DevelopmentSymmetric vs Asymmetric Division
12.01Page 21Immune System DevelopmentHematopoiesisHematopoietic Sites During DevelopmentSite Shifts Overview
12.01Page 23Immune System DevelopmentHematopoiesisHematopoietic Sites During DevelopmentBlood Islands of the Yolk Sac
12.01Page 24Immune System DevelopmentHematopoiesisHematopoietic Sites During DevelopmentHematogenesis vs Hematopoiesis
12.01Page 25Immune System DevelopmentHematopoiesisHematopoietic Sites During DevelopmentDefinitive HSCs — Dorsal Aorta
12.01Page 26Immune System DevelopmentHematopoiesisHematopoietic Sites During DevelopmentDorsal Aorta Live Imaging
12.01Page 27Immune System DevelopmentHematopoiesisHematopoietic Sites During DevelopmentHSC Migration Summary
12.01Page 32Immune System DevelopmentLymphoid Tissue DevelopmentLymphoid Organs Depend on Hematopoiesis
12.01Page 34Immune System DevelopmentPrimary Lymphoid OrgansBone MarrowColonization During Development
12.01Page 36Immune System DevelopmentPrimary Lymphoid OrgansBone MarrowHematopoietic Niche — Stroma and ECM
12.01Page 38Immune System DevelopmentPrimary Lymphoid OrgansBone MarrowOsteoblastic vs Vascular Niche
12.01Page 43Immune System DevelopmentHematopoietic DifferentiationDeterministic vs Stochastic Models
12.01Page 46Immune System DevelopmentHematopoietic DifferentiationTranscription Factors in Hematopoiesis
12.01Page 47Immune System DevelopmentHematopoietic DifferentiationCytokines and DifferentiationSCID-X and IL2Rγ
12.01Page 48Immune System DevelopmentHematopoietic DifferentiationCytokines and DifferentiationIL-2 Receptor Paradox
12.01Page 49Immune System DevelopmentHematopoietic DifferentiationCytokines and DifferentiationCommon Gamma Chain (γc)
12.01Page 51Immune System DevelopmentHematopoietic DifferentiationCytokines and DifferentiationEPO Feedback Loop
12.01Page 55Immune System DevelopmentClinical HematologyHSC TransplantationMyeloablative Conditioning
12.01Page 57Immune System DevelopmentClinical HematologyGene TherapySickle Cell Disease Gene Therapy
12.01Page 58Immune System DevelopmentClinical HematologyGene TherapyCRISPR Therapy — BCL11A Targeting
12.01Page 60Immune System DevelopmentLecture Summary
