12.07 · Immunité adaptative — tolérance et mémoire

Adaptive immunity — tolerance and memory

SMB4 Systèmes physiologiques 2 Immunologie, inflammation, transplantation · 21 pages

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Adaptive Immunity Overview

1Adaptive Immunity Overview

T-Cell Tolerance

Central Tolerance

2Positive and Negative Selection 3AIRE and Medullary Epithelial Cells 4AIRE and Tissue-Restricted Antigens 5AIRE Deficiency — APECED

Regulatory T Cells (Tregs)

6TCR Signal Strength and Treg Fate 7FOXP3 Identity and Treg Subtypes

8Central and Peripheral Tolerance Overview

Peripheral Tolerance

10Anergy — Missing Costimulation 11Treg Suppression Mechanisms 12IPEX Syndrome — FOXP3 Deficiency

13Tolerance Breakdown Mechanisms 14Type 1 Diabetes and Multiple Sclerosis

B-Cell Tolerance

15Central and Peripheral B-Cell Checkpoints

Immunological Memory

16Primary vs Secondary Response 17Memory Cell Generation in Primary Response

Memory T-Cell Subtypes

18Tcm, Tem, and Trm

Memory B Cells and Germinal Center

19Class Switching and Affinity Maturation

20Vaccine Types Overview 21Conjugate Vaccines and Adjuvants

12.07Page 1Adaptive Immunity Overview

Immunité adaptative — tolérance et mémoire page 1

12.07Page 2T-Cell ToleranceCentral TolerancePositive and Negative Selection

Immunité adaptative — tolérance et mémoire page 2

12.07Page 3T-Cell ToleranceCentral ToleranceAIRE and Medullary Epithelial Cells

Immunité adaptative — tolérance et mémoire page 3

12.07Page 4T-Cell ToleranceCentral ToleranceAIRE and Tissue-Restricted Antigens

Immunité adaptative — tolérance et mémoire page 4

12.07Page 5T-Cell ToleranceCentral ToleranceAIRE Deficiency — APECED

Immunité adaptative — tolérance et mémoire page 5

12.07Page 6T-Cell ToleranceRegulatory T Cells (Tregs)TCR Signal Strength and Treg Fate

Immunité adaptative — tolérance et mémoire page 6

12.07Page 7T-Cell ToleranceRegulatory T Cells (Tregs)FOXP3 Identity and Treg Subtypes

Immunité adaptative — tolérance et mémoire page 7

12.07Page 8T-Cell ToleranceCentral and Peripheral Tolerance Overview

Immunité adaptative — tolérance et mémoire page 8

12.07Page 9T-Cell ToleranceCentral and Peripheral Tolerance Overview

Immunité adaptative — tolérance et mémoire page 9

12.07Page 10T-Cell TolerancePeripheral ToleranceAnergy — Missing Costimulation

Immunité adaptative — tolérance et mémoire page 10

12.07Page 11T-Cell TolerancePeripheral ToleranceTreg Suppression Mechanisms

Immunité adaptative — tolérance et mémoire page 11

12.07Page 12T-Cell TolerancePeripheral ToleranceIPEX Syndrome — FOXP3 Deficiency

Immunité adaptative — tolérance et mémoire page 12

12.07Page 13AutoimmunityTolerance Breakdown Mechanisms

Immunité adaptative — tolérance et mémoire page 13

12.07Page 14AutoimmunityType 1 Diabetes and Multiple Sclerosis

Immunité adaptative — tolérance et mémoire page 14

12.07Page 15B-Cell ToleranceCentral and Peripheral B-Cell Checkpoints

Immunité adaptative — tolérance et mémoire page 15

12.07Page 16Immunological MemoryPrimary vs Secondary Response

Immunité adaptative — tolérance et mémoire page 16

12.07Page 17Immunological MemoryMemory Cell Generation in Primary Response

Immunité adaptative — tolérance et mémoire page 17

12.07Page 18Immunological MemoryMemory T-Cell SubtypesTcm, Tem, and Trm

Immunité adaptative — tolérance et mémoire page 18

12.07Page 19Immunological MemoryMemory B Cells and Germinal CenterClass Switching and Affinity Maturation

Immunité adaptative — tolérance et mémoire page 19

12.07Page 20VaccinesVaccine Types Overview

Immunité adaptative — tolérance et mémoire page 20

12.07Page 21VaccinesConjugate Vaccines and Adjuvants

Immunité adaptative — tolérance et mémoire page 21